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Serious morbidity associated with misuse of over-the-counter codeine–ibuprofen analgesics

Rozemary Karamatic, John Croese and Enrico Roche
Med J Aust 2011; 195 (9): 516.
doi:
10.5694/mja11.10463

To the Editor: The potential upper gastrointestinal morbidity associated with non-steroidal anti-inflammatory drug (NSAID) misuse is well known.1,2 Recently, Frei and colleagues3 provided an overview of the morbidity and patient characteristics relating to opioid–NSAID misuse; however, they did not identify those patients with NSAID ente

Rozemary Karamatic, Advanced Trainee in Gastroenterology1
John Croese, Senior Medical Officer, Gastroenterology and Hepatology2
Enrico Roche, Director of Gastroenterology1
1 Townsville Hospital, Townsville, QLD.
2 Royal Brisbane and Women’s Hospital, Brisbane, QLD.
Article References: 
Reference Text: 
Higuchi K, Umegaki E, Watanabe T, et al. Present status and strategy of NSAIDs-induced small bowel injury. J Gastroenterol 2009; 44: 879-888.
Reference Order: 
1
PubMed ID: 
19568687
Reference Text: 
Fortun PJ, Hawkey CJ. Non-steroidal anti-inflammatory drugs and the small intestine. Curr Opin Gastroenterol 2007; 23: 134-141.
Reference Order: 
2
PubMed ID: 
17268241
Reference Text: 
Frei MY, Nielsen S, Dobbin MDH, Tobin CL. Serious morbidity associated with the misuse of over-the-counter codeine–ibuprofen analgesics: a series of 27 cases. Med J Aust 2010; 193: 294-296.
Reference Order: 
3
PubMed ID: 
20819050
Reference Text: 
Matsumoto T, Kudo T, Esaki M, et al. Prevalence of non-steroidal anti-inflammatory drug-induced enteropathy determined by double-balloon endoscopy: a Japanese multicenter study. Scand J Gastroenterol 2008; 43: 490-496.
Reference Order: 
4
PubMed ID: 
18365915
Reference Text: 
Therapeutic Goods Administration. Codeine rescheduling — information for sponsors. 24 Feb 2010. http://www.tga.gov.au/industry/otc-codeine-rescheduling-100224.htm (accessed Sep 2011).
Reference Order: 
5
PubMed ID: 

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