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Neonatal vitamin D supplementation: are the protocols getting ahead of the evidence?

Kate M McCloskey, Natalie Wright, Anne-Louise Ponsonby and Peter J Vuillermin
Med J Aust 2011; 195 (11): 661. || doi: 10.5694/mja11.10493
Published online: 12 December 2011

To the Editor: We recently reviewed the individual policies of seven Australian tertiary maternity hospitals, from across all states, regarding neonatal vitamin D supplementation. An Australian 2006 consensus statement concerning the treatment and prevention of vitamin D deficiency in children and neonates identified the need to implement vitamin D supplementation in neonates born to mothers with serum 25-hydroxyvitamin D (25-OHD) levels of ≤ 50 nmol/L.1 Despite this, we found that a number of institutions have recently adopted a policy of treating infants of mothers with an antenatal serum 25-OHD level of < 75 nmol/L. Treatment of the neonate is with oral stoss therapy (50 000 IU vitamin D as a single dose) and/or daily oral vitamin D therapy (1000 IU) until cessation of breastfeeding. It should be noted that previous research has suggested that a substantial proportion of Australian women of childbearing age have a serum 25-OHD level < 75 nmol/L.2

  • Kate M McCloskey1
  • Natalie Wright1
  • Anne-Louise Ponsonby2
  • Peter J Vuillermin1

  • 1 Child Health Research Unit, Barwon Health, Melbourne, VIC.
  • 2 Murdoch Childrens Research Institute, Melbourne, VIC.


Competing interests:

No relevant disclosures.

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