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Scurvy and stroke: is there an association?

Felicity J Rose and Jonathan P Whitehead
Med J Aust 2011; 194 (9): 486.

To the Editor: We read with interest the recent letter by He and colleagues.1 The authors described a case of ischaemic stroke in a patient with scurvy and considered whether there was a connection between the two conditions.

Felicity J Rose, PhD Candidate
Jonathan P Whitehead, Team Leader
Department of Metabolic Medicine, Mater Medical Research Institute, Brisbane, QLD.
Article References: 
Reference Text: 
He EY, Wang LW, Kiernan MC. Scurvy and stroke: is there an association? Med J Aust 2010; 193: 555-556.
Reference Order: 
1
PubMed ID: 
21034393
Reference Text: 
Whitehead JP, Richards AA, Hickman IJ, et al. Adiponectin — a key adipokine in the metabolic syndrome. Diabetes Obes Metab 2006; 8: 264-280.
Reference Order: 
2
PubMed ID: 
16634986
Reference Text: 
Nishimura M, Izumiya Y, Higuchi A, et al. Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms. Circulation 2008; 117: 216-223.
Reference Order: 
3
PubMed ID: 
18158361
Reference Text: 
Szmitko PE, Teoh H, Stewart DJ, Verma S. Adiponectin and cardiovascular disease: state of the art? Am J Physiol Heart Circ Physiol 2007; 292: H1655-H1663.
Reference Order: 
4
PubMed ID: 
17142348
Reference Text: 
Rose FJ, Webster J, Barry JB, et al. Synergistic effects of ascorbic acid and thiazolidinedione on secretion of high molecular weight adiponectin from human adipocytes. Diabetes Obes Metab 2010; 12: 1084-1089.
Reference Order: 
5
PubMed ID: 
20977580

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