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A case of discordant HbA1c: a method-dependent error

Goce Dimeski, Carel J Pretorius, Anthony W Russell, Stephen P Miller, Robert J Bird and Jacobus P J Ungerer
Med J Aust 2009; 191 (6): 347-349.

Although glycated haemoglobin (HbA1c) has become the key biochemical marker of long-term glycaemic control, analytical method-dependent differences in results can occur when haemoglobin variants are present or HbA1c is reduced by decreased red cell survival.

Goce Dimeski, BSc, Supervising Scientist of Chemical Pathology, Princess Alexandra Hospital1
Carel J Pretorius, MB ChB, FCPathChem(SA), Chemical Pathologist1
Anthony W Russell, MB BS, FRACP, PhD, Director of Diabetes and Endocrinology,2 and Research Fellow3
Stephen P Miller, BSc, Haematology Scientist, Royal Brisbane Hospital1
Robert J Bird, MB BS, FRCP(Lon), FRCPA, Director of Haematology, Princess Alexandra Hospital1
Jacobus P J Ungerer, MB BS, MMed(ChemPath), FRCPA, Director of Chemical Pathology1
1 Pathology Queensland, Brisbane, QLD.
2 Princess Alexandra Hospital, Brisbane, QLD.
3 Diamantina Institute for Cancer, Immunology and Metabolic Medicine, University of Queensland, Brisbane, QLD.
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