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Tissue plasminogen activator for acute ischaemic stroke

Julia J Batmanian, Meeyin Lam, Caitlin Matthews, Andrew Finckh, Martin Duffy, Robert Wright, Bruce J Brew and Romesh Markus
Med J Aust 2008; 188 (8): 489-490.
Published online: 21 April 2008

In reply: We welcome the opportunity to respond to issues raised by Hurley and Toncich. Australian, United States and European stroke guidelines based on level 1, grade A evidence recommend intravenous recombinant tissue plasminogen activator (IV-rtPA) for patients with acute ischaemic stroke (AIS) who meet specific inclusion criteria and present within 3 hours of AIS onset.1,2 Recombinant tPA is approved for this indication by the Therapeutic Goods Administration.

  • Julia J Batmanian1
  • Meeyin Lam1
  • Caitlin Matthews1
  • Andrew Finckh1
  • Martin Duffy1
  • Robert Wright1
  • Bruce J Brew2,1
  • Romesh Markus1,2

  • 1 St Vincent’s Hospital, Sydney, NSW.
  • 2 University of New South Wales, Sydney, NSW.

Correspondence: rmarkus@stvincents.com.au

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