Is it unethical to avoid using all available information to monitor drug safety?
Adverse effects of health care have recently been in the news, from the worrying unexpected cardiovascular risks associated with use of the cyclooxygenase-2 inhibitor rofecoxib (Vioxx) to reports of high percentages of complications following routine surgery.1,2 As medical care becomes more complex, sophisticated and expensive in Australia, it is paramount that we have the best systems in place to monitor its impact and evaluate its safety and efficacy.
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- 2. Gottliebsen R, Pirani C. Failure rate of surgery reaches 20pc. The Australian 2006; 11 Nov: 1. http://www.theaustralian.news.com.au/story/0,20867,20737900-601,00.html (accessed Jan 2007).
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- 4. Stanley FJ, Croft ML, Gibbins J, Read AW. A population database for maternal and child health research in Western Australia using record linkage. Paediatr Perinat Epidemiol 1994; 8: 433-447.
- 5. Brook EL, Rosman DL, Holman CDJ, Trutwein B. Summary report: research outputs project, WA Data Linkage Unit (1995–2003). Perth: WA Data Linkage Unit, 2005. http://www.publichealth.uwa.edu.au/__data/page/63033/ROP_SUMMARY3.pdf (accessed Jan 2007).
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- 8. Baciu AS, Stratton K, Burke SP, editors; Committee on the Assessment of the US Drug Safety System. The future of drug safety: promoting and protecting the health of the public. Washington, DC: The National Academies Press, 2006. http://www.nap.edu/catalog/11750.html (accessed Jan 2007).
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