MJA
MJA InSight
MJA Careers
Letters

Systemic allergy to topical hexamidine

Raymond J Mullins
Med J Aust 2006; 185 (3): 177.

To the Editor: Food, medication or insect stings are the major causes of systemic allergic reactions.1 That topical agents can mimic such reactions is not commonly appreciated. I report here a systemic allergic reaction to a topical medication (initially attributed to food).

Raymond J Mullins, PhD, FRACP, FRCPA, Clinical Immunologist
John James Medical Centre, Canberra, ACT.
Article References: 
Reference Text: 
Golden DB. Patterns of anaphylaxis: acute and late phase features of allergic reactions. Novartis Found Symp 2004; 257: 101-110; discussion 110-115, 157-160, 276-285.
Reference Order: 
1
PubMed ID: 
15025394
Reference Text: 
Perrine D, Chenu JP, Georges P, et al. Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga. Antimicrob Agents Chemother 1995; 39: 339-342.
Reference Order: 
2
PubMed ID: 
7726493
Reference Text: 
Revuz J, Poli F, Wechsler J, Dubertret L. [Contact dermatitis from hexamidine] [French]. Ann Dermatol Venereol 1984; 111: 805-810.
Reference Order: 
3
PubMed ID: 
6517448
Reference Text: 
Krautheim AB, Jermann TH, Bircher AJ. Chlorhexidine anaphylaxis: case report and review of the literature. Contact Dermatitis 2004; 50: 113-116.
Reference Order: 
4
PubMed ID: 
15153122
Reference Text: 
Guillet G, Guillet MH, Dagregorio G. Allergic contact dermatitis from natural rubber latex in atopic dermatitis and the risk of later Type I allergy. Contact Dermatitis 2005; 53: 46-51.
Reference Order: 
5
PubMed ID: 
15982232

The full contents of this page are only available to subscribers.