Microscopic colitis associated with exposure to lansoprazole

Sarah N Hilmer, Timothy R Heap, Robert P Eckstein, Gillian M Shenfield and Christopher S Lauer
Med J Aust 2006; 184 (4): 185-186.

Clinical record

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  • Sarah N Hilmer1
  • Timothy R Heap2
  • Robert P Eckstein3
  • Gillian M Shenfield4
  • Christopher S Lauer5

  • 1 Royal North Shore Hospital, Sydney, NSW.
  • 2 Missenden Road Medical Centre, Sydney, NSW.


Competing interests:

None identified.

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  • 4. Price AB. Pathology of drug-associated gastrointestinal disease. Br J Clin Pharmacol 2003; 56: 477-482.
  • 5. Mukherjee S. Diarrhea associated with lansoprazole. J Gastroenterol Hepatol 2003; 18: 602-603.
  • 6. Thomson RD, Lestina LS, Bensen SP, et al. Lansoprazole-associated microscopic colitis: a case series. Am J Gastroenterol 2002; 97: 2908-2913.
  • 7. Wilcox GM, Mattia A. Collagenous colitis associated with lansoprazole. J Clin Gastroenterol 2002; 34: 164-166.
  • 8. Besancon M, Simon A, Sachs G, Shin JM. Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents. J Biol Chem 1997; 272: 22438-22446.
  • 9. Kaunitz JD, Sachs G. Identification of a vanadate-sensitive potassium-dependent proton pump from rabbit colon. J Biol Chem 1986; 261: 14005-14010.
  • 10. Natsch S, Vinks MH, Voogt AK, et al. Anaphylactic reactions to proton-pump inhibitors. Ann Pharmacother 2000; 34: 474-476.


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