Subgroup analysis: application to individual patient decisions

R John Simes, Val J Gebski and Anthony C Keech
Med J Aust 2004; 180 (9): . || doi: 10.5694/j.1326-5377.2004.tb06027.x
Published online: 3 May 2004

Clinical trials provide evidence of effectiveness of treatments as an average for a group of patients, yet, in clinical medicine, we usually wish to apply these results to individuals. Can we simply apply the overall trial result for each patient, or can the result be tailored to individual patients in some way?

  • R John Simes1
  • Val J Gebski2
  • Anthony C Keech3

  • NHMRC Clinical Trials Centre, Camperdown, NSW.


Competing interests:

None identified.


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