Objective: 1. To determine whether
naltrexone-accelerated detoxification with minimal sedation is an
acceptable and effective form of induction onto naltrexone. 2. To
monitor outcomes of detoxified patients.
Design: Observational study.
Setting: Medical ward of a general hospital (for detoxification) and a community clinic (for follow-up) in Sydney, NSW, 1998.
Patients: 15 heroin users and 15 people seeking withdrawal from methadone.
Intervention: Detoxification used naltrexone (12.5 or