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Precision medicine in Australia: now is the time to get it right

Rosie O'Shea, Alan Ma, Robyn Jamieson and Nicole M Rankin
Med J Aust 2023; 218 (7): . || doi: 10.5694/mja2.51889
Published online: 17 April 2023

In reply: We thank Nindra and colleagues1 for their commentary on our call to action2 regarding the need for an implementation science research approach to translation of precision medicine into the health care system. Although we acknowledge that access to laboratory genomic testing is vital for precision medicine, there are additional broader systemic issues that also need to be managed in research and planning to ensure scalability, equity of access, and success.


  • 1 University of Sydney, Sydney, NSW
  • 2 Children's Medical Research Institute, Sydney, NSW
  • 3 Children's Hospital at Westmead, Sydney, NSW
  • 4 Centre for Health Policy, University of Melbourne, Melbourne, VIC


Correspondence: rosie.oshea@sydney.edu.au

Acknowledgements: 

Alan Ma is the recipient of a Sydney Health Partners’ Research Translation Fellowship (https://sydneyhealthpartners.org.au/work‐with‐us/research‐translation‐fellowships), which funds part of his clinical time to perform implementation science based research in genomics. The funding source has no designated role in planning, running, design, data collection, analysis, interpretation, reporting or publications.

Competing interests:

No relevant disclosures.

  • 1. Nindra U, Pal A, Lee CS. Precision medicine in Australia: now is the time to get it right [letter]. Med J Aust 2023; 218: 330‐331.
  • 2. O'Shea R, Ma AS, Jamieson RV, Rankin NM. Precision medicine in Australia: now is the time to get it right. Med J Aust 2022; 217: 559‐563. https://www.mja.com.au/journal/2022/217/11/precision‐medicine‐australia‐now‐time‐get‐it‐right
  • 3. AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discov 2017; 7: 818‐831.
  • 4. Katlic MR, Facktor MA, Berry SA, et al. ProvenCare lung cancer: a multi‐institutional improvement collaborative. CA Cancer J Clin 2011; 61: 382‐396.
  • 5. Vetsch J, Wakefield CE, Techakesari P, et al. Healthcare professionals’ attitudes toward cancer precision medicine: a systematic review. Semin Oncol 2019; 46: 291‐303.

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