Acute macular neuroretinopathy

Sarah Chan
Med J Aust 2020; 213 (4): . || doi: 10.5694/mja2.50614
Published online: 17 August 2020

A 23‐year‐old woman was referred to the ophthalmology clinic with sudden onset unilateral paracentral scotomas. She does not take any medications and has no significant ocular or medical history apart from recent influenza‐like illness. Although fundus examination was unremarkable (Figure, A), infrared imaging with optical coherence tomography revealed dark grey petalloid perifoveal lesions (Figure, B). She was diagnosed with acute macular neuroretinopathy (AMN), which has an unknown pathophysiology and aetiology but is known to be associated with fever, influenza, upper respiratory tract infections, and use of the oral contraceptive pill, mostly affecting young Caucasian females.1,2 As these scotomas persist indefinitely, clinicians should be aware of the possibility of AMN.1,2

  • Royal Brisbane and Women's Hospital, Brisbane, QLD

Competing interests:

No relevant disclosures

  • 1. Bos PJ, Deutman AF. Acute macular neuroretinopathy. Am J Ophthalmol 1975; 80: 573–584.
  • 2. Bhavsar KV, Lin S, Rahimy E, et al. Acute macular neuroretinopathy: a comprehensive review of the literature. Surv Ophthalmol 2016; 61: 538–565.


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