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- Joanne Joseph1,2
- David Rabbolini3,4
- Anoop K Enjeti5
- Emmanuel Favaloro6,7
- Marie‐Christine Kopp4
- Simon McRae8
- Leonardo Pasalic6,7
- Chee Wee Tan8
- Christopher M Ward3,4
- Beng H Chong9
- 1 St Vincent's Hospital, Sydney, NSW
- 2 St Vincent's Clinical School, University of New South Wales, Sydney, NSW
- 3 Royal North Shore Hospital, Sydney, NSW
- 4 Northern Blood Research Centre, Kolling Institute of Medical Research, Sydney, NSW
- 5 Calvary Mater Hospital, Sydney, NSW
- 6 Institute of Clinical Pathology and Medical Research, Sydney, NSW
- 7 Westmead Hospital, Sydney, NSW
- 8 Royal Adelaide Hospital, Adelaide, SA
- 9 St George Hospital, Sydney, NSW
Anoop Enjeti has received speaker fees from Bayer and Sanofi Aventis outside the submitted work. Simon McRae has received research funding from CSL and Roche outside the submitted work. Chee Wee Tan has received non‐financial support from Bayer Health and speaker fees from Pfizer outside the submitted work. Christopher Ward has received personal fees and non‐financial support from Aspen, personal fees from Instrumentation Laboratory (Werfen) and personal fees from Sanofi during the preparation of this consensus statement.
Abstract
Introduction: Heparin‐induced thrombocytopenia (HIT) is a prothrombotic disorder that occurs following the administration of heparin and is caused by antibodies to platelet factor 4 and heparin. Diagnosis of HIT is essential to guide treatment strategies using non‐heparin anticoagulants and to avoid unwanted and potential fatal thromboembolic complications. This consensus statement, formulated by members of the Thrombosis and Haemostasis Society of Australia and New Zealand, provides an update on HIT pathogenesis and guidance on the diagnosis and management of patients with suspected or confirmed HIT.
Main recommendations:
Changes in management as a result of this statement: