Neurofibromatosis of the tongue

Basile N Landis and Urs Borner
Med J Aust 2016; 205 (7): . || doi: 10.5694/mja16.00549
Published online: 3 October 2016

A 45-year-old woman presented with a painless mass in the tongue that had grown gradually over the past 20 years (Figure, arrowheads). She had café-au-lait spots and previous neurofibroma resections. Neurofibromatosis type 1 was also found in her father and two children. Recent speech problems made a resection necessary. Partial removal of the mass immediately improved communication. Pathological analysis showed plexiform neurofibroma without malignant transformation. Neurofibromatosis type 1 is an autosomal dominant disorder characterised by neurofibromas that can potentially affect every site of the body. Malignant transformation is rare and resection is indicated when functional or aesthetic impairment is associated.1

  • 1 Hôpitaux Universitaires de Genève, Geneva, Switzerland
  • 2 HNO-ORL Inselspital Universitätsspital Bern, Bern, Switzerland


  • 1. Hirbe AC, Gutmann DH. Neurofibromatosis type 1: a multidisciplinary approach to care. Lancet Neurol 2014; 13: 834-843.


remove_circle_outline Delete Author
add_circle_outline Add Author

Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.