Methylisothiazolinone in baby wipes: a rising star among causes of contact dermatitis

Jennifer L Cahill, Ryan W Toholka and Rosemary L Nixon
Med J Aust 2014; 200 (4): . || doi: 10.5694/mja13.10946
Published online: 3 March 2014

To the Editor: Methylisothia-zolinone (MI) is a preservative that has been used alone in cosmetic and personal products since the early 2000s.1 Before that time, MI was combined with methylchloroiso-thiazolinone in the widely used preservative Kathon CG (Dow Chemical Company), in a 1:3 ratio with the concentration of MI limited to 3.75 parts per million. This limit was subsequently increased to 100 parts per million, and MI is now being widely used in consumer products.

  • Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation Inc, Melbourne, VIC.


Competing interests:

No relevant disclosures.

  • 1. Lundov MD, Krongaard T, Menné TL, Johansen JD. Methylisothiazolinone contact allergy: a review. Br J Dermatol 2011; 165: 1178-1182.
  • 2. Geier J, Lessmann H, Schnuch A, Uter W. Recent increase in allergic reactions to methylchloroisothiazolinone/methylisothiazolinone: is methylisothiazolinone the culprit? Contact Dermatitis 2012; 67: 334-341.
  • 3. McFadden JP, Mann J, White JM, et al. Outbreak of methylisothiazolinone allergy targeting those aged 40 years. Contact Dermatitis 2013; 69: 53-55.
  • 4. Boyapati A, Tam M, Tate B, et al. Allergic contact dermatitis to methylisothiazolinone: exposure from baby wipes causing hand dermatitis. Australas J Dermatol 2013; 54: 264-267.


remove_circle_outline Delete Author
add_circle_outline Add Author

Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.