Excessive consumption of vitamin K1-rich foods may antagonise the action of warfarin. Eating a large amount of brussels sprouts precipitated hospital admission for a patient who was on anticoagulation therapy for a left ventricular assist device. Doctors should counsel all patients in whom maintenance of anticoagulation is crucial against overconsumption of such foods.
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The hazards of brussels sprouts consumption at Christmas
Stephen J Pettit, Alan G Japp and Roy S Gardner
Med J Aust 2012; 197 (11): 661-662.
Stephen J Pettit, MB BS, PhD, MRCP, Registrar
Alan G Japp, MB ChB, PhD, MRCP, Registrar
Roy S Gardner, MB ChB, MD, MRCP, Cardiologist
US Department of Agriculture, Agricultural Research Service. USDA national nutrient database for standard reference, release 25. 2012. http://www.ars.usda.gov/ba/bhnrc/ndl (accessed Nov 2012).
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Suvarna R, Pirmohamed M, Henderson L. Possible interaction between warfarin and cranberry juice. BMJ 2003; 327: 1454.
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