Australasian Society for Infectious Diseases guidelines for the diagnosis and treatment of Clostridium difficile infection

Allen C Cheng, John K Ferguson, Michael J Richards, Jennifer M Robson, Gwendolyn L Gilbert, Alistair McGregor, Sally Roberts, Tony M Korman and Thomas V Riley
Med J Aust 2011; 194 (7): 353-358.
  • Allen C Cheng1,2
  • John K Ferguson3,4
  • Michael J Richards5,6
  • Jennifer M Robson7
  • Gwendolyn L Gilbert8
  • Alistair McGregor9
  • Sally Roberts10
  • Tony M Korman11
  • Thomas V Riley12,13

  • 1 Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC.
  • 2 Infectious Diseases Unit, Alfred Hospital, Melbourne, VIC.
  • 3 John Hunter Hospital, Newcastle, NSW.
  • 4 University of Newcastle, Newcastle, NSW.
  • 5 Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, VIC.
  • 6 University of Melbourne, Melbourne, VIC.
  • 7 Sullivan Nicolaides Pathology, Brisbane, QLD.
  • 8 Centre for Infectious Diseases and Microbiology, Institute of Clinical Pathology and Medical Research, Sydney, NSW.
  • 9 Royal Hobart Hospital, Hobart, TAS.
  • 10 Clinical Microbiology Laboratory, LabPlus, Auckland District Health Board, Auckland, NZ.
  • 11 Infectious Diseases, Monash Medical Centre, Melbourne, VIC.
  • 12 Microbiology and Immunology, University of Western Australia, Perth, WA.
  • 13 Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA.



We thank Anton Peleg, Paul Johnson, Chris Lemoh, Kate Cherry, Gerhard Weldhagen, Craig Boutlis, Helen Van Gessel, Raymond Chan, Karen Rowland, David Mitchell and Gillian Wood for comments on an earlier draft of the guidelines. We also thank Ian Civil, Deirdre Mansell and Michael Grigg at the Royal Australasian College of Surgeons for their review.

Competing interests:

Allen Cheng received support from the Australian Commission for Safety and Quality in Healthcare for travel to present these guidelines. Tony Korman is on the advisory boards of Pfizer, AstraZeneca, Janssen-Cilag and Novartis, and has received payment for speaking at a Novartis-sponsored symposium in 2010 and for chairing meetings for Novartis and Janssen-Cilag in 2009. Thomas Riley has been on the advisory boards of Merck and Genzyme in relation to C. difficile treatment, is involved in research evaluating products in relation to C. difficile diagnosis and treatment that is funded by Bayer, bioMérieux, Becton Dickinson and Oxoid, and has received speakers’ fees from these companies.

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