Twenty-five patients living in a tick-endemic region of Sydney, New South Wales developed red meat allergy after experiencing large local reactions to tick bites. This represents a potentially novel cross-reaction between an arthropod and a food protein.
Between 2003 and 2007, 25 patients (seven men, 18 women; mean age [range], 29.9 [21–63] years) presented to our allergy practice in Sydney, New South Wales with a history of an allergic reaction to red meat.
- 1. Gauci M, Loh RKS, Stone BF, Thong YH. Allergic reactions to the Australian paralysis tick, Ixodes holocyclus: diagnostic evaluation by skin test and radioimmunoassay. Clin Exp Allergy 1989; 19: 279-283.
- 2. Werfel SJ, Cooke SK, Sampson HA. Clinical reactivity to beef in children allergic to cow’s milk. J Allergy Clin Immunol 1997; 99: 293-300.
- 3. Drouet M, Boutet S, Lauret MG, et al. [The pork–cat syndrome or crossed allergy between pork meat and cat epithelia (I)] [French]. Allerg Immunol (Paris) 1994; 26: 166-168, 171-172.
- 4. Sabbah A, Rousseau C, Lauret MG, Drouet M. [The pork–cat syndrome: RAST inhibition test with Feld One] [French]. Allerg Immunol (Paris) 1994; 26: 259-260.
- 5. Storer E, Sheridan AT, Warren L, Wayte J. Ticks in Australia. Australas J Dermatol 2003; 44: 83-89.
- 6. Metz M, Piliponsky AM, Chen CC, et al. Mast cells can enhance resistance to snake and honeybee venoms. Science 2006; 313: 526-530.
- 7. Fiocchi A, Restani P, Riva E, et al. Meat allergy: I — Specific IgE to BSA and OSA in atopic, beef sensitive children. J Am Coll Nutr 1995; 14: 239-244.
- 8. Commins S, Lucas S, Hosen J, et al. Anaphylaxis and IgE antibodies to galactose-alpha-1,3-galactose (alphaGal): insight from the identification of novel IgE ab to carbohydrates on mammalian proteins [abstract]. J Allergy Clin Immunol 2008; 121 Suppl 1: S25.
- 9. Chung CH, Mirakhur B, Chan E, et al. Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. N Engl J Med 2008; 358: 1109-1117.
- 10. Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med 2003; 348: 977-985.
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