Guidelines for the use of infant formulas to treat cows milk protein allergy: an Australian consensus panel opinion

Andrew S Kemp, David J Hill, Katrina J Allen, Kym Anderson, Geoffrey P Davidson, Andrew S Day, Ralph G Heine, Jane E Peake, Susan L Prescott, Albert W Shugg and John K Sinn
Med J Aust 2008; 188 (2): 109-112.
  • Andrew S Kemp1
  • David J Hill2
  • Katrina J Allen3
  • Kym Anderson4
  • Geoffrey P Davidson5
  • Andrew S Day6
  • Ralph G Heine3,7
  • Jane E Peake8
  • Susan L Prescott9
  • Albert W Shugg10
  • John K Sinn11

  • 1 Department of Allergy and Immunology, Children’s Hospital at Westmead, Sydney, NSW.
  • 2 Murdoch Childrens Research Institute, Royal Children’s Hospital, Melbourne, VIC.
  • 3 Department of Allergy and Clinical Immunology, Royal Children’s Hospital, Melbourne, VIC.
  • 4 Alice Springs Hospital, Alice Springs, NT.
  • 5 Department of Gastroenterology, Women’s and Children’s Hospital, Adelaide, SA.
  • 6 Department of Gastroenterology, Sydney Children’s Hospital, Sydney, NSW.
  • 7 Department of Gastroenterology and Clinical Nutrition, Royal Children’s Hospital, Melbourne, VIC.
  • 8 Department of Paediatrics and Child Health, University of Queensland, Royal Children’s Hospital, Brisbane, QLD.
  • 9 School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital, Perth, WA.
  • 10 University of Tasmania Rural Clinical School, Burnie, TAS.
  • 11 Department of Neonatology, Royal North Shore Hospital, Sydney, NSW.



The panel gratefully acknowledges the support of SHS/Nutricia, which funded the teleconferences and face-to-face meetings for the preparation of this consensus. None of the panel members received any remuneration for their participation.

Competing interests:

Andrew Kemp has spoken at a clinical update sponsored by Nutricia and received a speaker fee, and his department has held a clinical update meeting sponsored by Abbott. David Hill has received support from SHS/Nutricia for clinical research, to attend scientific meetings, for consultations and to speak at sponsored meetings. Ralph Heine has been a member of the scientific advisory boards of Nutricia Australia and the Nestlé Nutrition Institute Oceania, and has received travel assistance and speaker fees from both companies to present at or attend scientific meetings. Jane Peake has been a speaker at meetings sponsored by SHS/Nutricia, Nestlé and Wyeth, and has had some travel expenses reimbursed. Susan Prescott has received an honorarium from Mead Johnson and is a member of the independent Scientific Advisory Board of Nestlé.

  • 1. Kemp A. Hypoallergenic formula prescribing practices in Australia. J Paediatr Child Health 2006; 42: 191-195.
  • 2. American Academy of Pediatrics, Committee on Nutrition. Hypoallergenic infant formulas. Pediatrics 2000; 106: 346-349.
  • 3. Agostoni C, Axelsson I, Goulet O, et al. Soy protein infant formulae and follow-on formulae: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2006; 42: 352-361.
  • 4. Vandenplas Y, Brueton M, Dupont C, et al. Guidelines for the diagnosis and management of cows milk protein allergy in infants. Arch Dis Child 2007; 92: 902-908.
  • 5. Heine RG, Elsayed S, Hosking CS, Hill DJ. Cows milk allergy in infancy. Curr Opin Allergy Clin Immunol 2002; 2: 217-225.
  • 6. Johansson SG, Bieber T, Dahl R, et al. Revised nomenclature for allergy for global use: report of the Nomenclature Review Committee of the World Allergy Organization, 2003. J Allergy Clin Immunol 2004; 113: 832-836.
  • 7. Muraro MA, Giampietro PG, Galli E. Soy formulas and nonbovine milk. Ann Allergy Asthma Immunol 2002; 89: 97-101.
  • 8. Vanderhoof JA, Murray ND, Kaufman SS, et al. Intolerance to protein hydrolysate infant formulas: an underrecognized cause of gastrointestinal symptoms in infants. J Pediatr 1997; 131: 741-744.
  • 9. Sampson HA. Update on food allergy. J Allergy Clin Immunol 2004; 113: 805-819.
  • 10. Nowak-Wegrzyn A, Sampson HA, Wood RA, Sicherer SH. Food protein-induced enterocolitis syndrome caused by solid food proteins. Pediatrics 2003; 111: 829-835.
  • 11. Niggemann B, Sielaff B, Beyer K, et al. Outcome of double-blind, placebo-controlled food challenge tests in 107 children with atopic dermatitis. Clin Exp Allergy 1999; 29: 91-96.
  • 12. Iacono G, Carroccio A, Cavataio F, et al. Gastroesophageal reflux and cows milk allergy in infants: a prospective study. J Allergy Clin Immunol 1996; 97: 822-827.
  • 13. Chehade M, Magid MS, Mofidi S, et al. Allergic eosinophilic gastroenteritis with protein-losing enteropathy: intestinal pathology, clinical course, and long-term follow-up. J Pediatr Gastroenterol Nutr 2006; 42: 516-521.
  • 14. Savilahti E. Food-induced malabsorption syndromes. J Pediatr Gastroenterol Nutr 2000; 30 Suppl: S61-S66.
  • 15. Iacono G, Cavataio F, Montalto G, et al. Intolerance of cows milk and chronic constipation in children. N Engl J Med 1998; 339: 1100-1104.
  • 16. Lucassen PL, Assendelft WJ. Systematic review of treatments for infant colic. Pediatrics 2001; 108: 1047-1048.
  • 17. Lake AM. Food-induced eosinophilic proctocolitis. J Pediatr Gastroenterol Nutr 2000; 30 Suppl: S58-S60.
  • 18. Liacouras CA, Eosinophilic esophagitis: treatment in 2005. Curr Opin Gastroenterol 2006; 22: 147-152.


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