Macrophagic myofasciitis associated with vaccine-derived aluminium

Meena Shingde, Roger Pamphlett, James Hughes, Ross Boadle and Edward J Wills
Med J Aust 2005; 183 (3): 145-146.

Macrophagic myofasciitis is characterised by sheets of macrophages in striated muscle, a few lymphocytes and inconspicuous muscle fibre damage. It is due to aluminium contained in vaccines, and is localised to the inoculation site. We report the first Australian case, detected incidentally when investigating a raised serum creatine kinase level.

Clinical record

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  • Meena Shingde1
  • Roger Pamphlett2
  • James Hughes3
  • Ross Boadle4
  • Edward J Wills5

  • 1 Department of Pathology, University of Sydney, Sydney, NSW.
  • 2 Tamworth, NSW.
  • 3 Electron Microscopy Unit, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Sydney, NSW.
  • 4 Central Sydney Electron Microscopy Unit, Concord Hospital, Concord, NSW.


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