Connect
MJA
MJA

Making sense of trial results: outcomes and estimation

Rachel L O'Connell, Val J Gebski and Anthony C Keech
Med J Aust 2004; 180 (3): 128-130.
Published online: 2 February 2004

The format in which the results of randomised controlled trials (RCTs) are presented can have a major impact on how they are interpreted, and the extent to which they will be adopted into clinical practice. A key element in the reporting of RCTs is the measurement scale on which outcomes are assessed. Scales which are presented as large whole numbers tend to attract the interest of clinicians and patients, independent of the reliability of the estimates.1,2 Enough information needs to be presented to allow clinicians to convert the size of the reported benefit into a format which allows easy comparison with other relevant trial results, including the range of certainty of the benefit (Box 1).3 As outcomes may be measured and collected in a variety of ways, it is essential that there is prior agreement on how any benefit or detriment of the intervention will be reported.

  • Rachel L O'Connell1
  • Val J Gebski2
  • Anthony C Keech3

  • NHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW.

Correspondence: 

Competing interests:

None identified.

Author

remove_circle_outline Delete Author
add_circle_outline Add Author

Comment
Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Responses are now closed for this article.