To the Editor: Serotonin toxicity is an under-recognised, potentially fatal syndrome that is becoming more common as the use of serotonergic drugs increases.1 We report a case of serotonin toxicity following the concomitant use of the antidepressant citalopram and methylene blue.
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- Southmead Hospital, Bristol, United Kingdom.
Correspondence: john.whitaker@trinity-oxford.com
- 1. Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med 2005; 352: 1112-1120.
- 2. Ramsay RR, Dunford C, Gillman PK. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. Br J Pharmacol 2007; 152: 946-951.
- 3. Kartha SS, Chacko CE, Bumpous JM, et al. Toxic metabolic encephaolopathy after parathyroidectomy with methylene blue localization. Otolaryngol Head Neck Surg 2006; 135: 765-768.
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