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18 February 2008

Meningococcal vaccine

A novel tetravalent meningococcal vaccine appears to be safe and effective in infants, according to the results of a British and Canadian randomised controlled trial.

JAMA 2008; 299: 173-184

Free falling

Multifactorial programs aimed at preventing falls in older people appear to have limited effectiveness, say UK researchers.

BMJ 2008; 336: 130-133

Publication bias and antidepressant trials

Selective publication of clinical trials has come under fire from a group of US researchers and clinicians. Reviews from the US Food and Drug Administration (FDA) for studies of 12 antidepressant agents were obtained and matched with published studies via a systematic literature review.

N Engl J Med 2008; 358: 252-260

Steroids for stiffness

Modified-release prednisone appears to provide a clinically useful reduction in morning stiffness in patients with rheumatoid arthritis compared with standard preparations of the glucocorticoid.

Lancet 2008; 371: 205-214

 

MRSA in USA

Multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus (MRSA) appears to be an emerging infection in men who have sex with men, a US study has shown.

Ann Intern Med 2008; Jan 14 [Epub ahead of print]

Dr Tanya Grassi, MJA

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