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Editorials

Evidence into practice: the mental health hurdle is high

Ian B Hickie and Grant A Blashki
MJA 2006; 184 (11): 542-543

Guidelines for GPs need to tackle the tough issues

These are interesting times in Australian mental health. On a daily basis, the gap between best practice guidelines and the quality of services delivered widens. Rapid advances in clinical neurosciences give us real enthusiasm for new approaches to treatment. By contrast, national and state-based inquiries highlight fundamental failures in acute and ongoing care. Although major service redevelopments continue, we do not yet provide an integrated health services response. All our governments now concede that a new round of investment, innovation and coordinated reform is essential. Substantial new investments are justified and necessary if we are to see genuine innovation, improved access to care, and better health outcomes in the mental health service environment.

The production of guidelines for bipolar disorder internationally reflects the therapeutic gains that should be available for people with this common and disabling illness.1,2 However, when guidelines target general practitioners, like the recommendations provided by Mitchell et al in this issue of the Journal (The management of bipolar disorder in general practice),3 some hard questions need to be asked. Are they relevant to general practice in Australia? Do they connect with the target audience? Are the recommendations achievable in our health care environment?

In recent years, most GPs feel that they have received truck loads of worthy guidelines from their specialist colleagues. Although guidelines are critical to improving health care quality, in the end most fail to recommend strategies that lead to real impacts on clinical practice. The mental health field is no exception. It too is awash with new guidelines.4 Surprisingly, given that 75% of mental health consultations take place in the primary care environment, few have targeted general practice. A notable exception is the guidelines for the treatment of depression in general practice settings, commissioned by beyondblue: the national depression initiative.5

From a GP’s perspective, most mental health guidelines don’t concede basic service limitations. First, GPs are not an unlimited mental health resource. In fact, recent data indicate a major slowing in the rate of increase in the treatment of common mental disorders in primary care settings.6 Second, mental health guidelines compete with all other medical guidelines for attention. Simply producing more guidelines for more disorders doesn’t increase the likelihood that recommendations will be put into action. Producing more guidelines for closely related topics (eg, bipolar depression,3 major depression in specialist settings,7 major depression in primary care,5 youth depression8) also doesn’t help. Third, simply extrapolating evidence from studies conducted in patients with severe, chronic or complex disorders encountered in specialist treatment centres may not only be scientifically questionable, but may particularly annoy GPs.9

Most importantly, “GP guidelines” for mental disorders should deal explicitly with the key issues: identification of less severe forms of the disorder; management of medical comorbidity; overlap with alcohol and substance misuse; limited geographical and economic access to specialist psychological support; use of alternative treatments for less severe or less complex cases; and implications of poor access to specialist assessment during acute phases of illness. Providing a detailed list of reasons for specialist referral does not assist those GPs who struggle on a daily basis to connect with any specialist support in the private or public sector.

Rather than addressing such issues, specialist psychiatry has a particular knack for creating more disorders, more subcategories and more complex treatment regimens.1-3 The self-explanatory nature of manic-depressive illness has been replaced by the more opaque terms “bipolar I”, “bipolar II”, “bipolar depression”, “mixed episodes”, “rapid cycling”, and “cyclothymia”. However, if such fine-grained differentiation is not associated with quite specific differences in treatment or prognosis, or is not based on a solid evidence base,10 then it holds little appeal.

The medical, psychosocial and legal consequences of a GP making a diagnosis of bipolar disorder are potentially considerable. To suggest that these can be minimised by having all such decisions reviewed by a specialist is highly optimistic, especially given the decreasing availability and inequitable access to such resources. While recent improved access to psychological therapies through partnerships in general practice,11 and proposed direct referral mechanisms to clinical psychologists,12 are most welcome, it is not yet clear whether these developments will increase access for patients with bipolar disorder to the more intensive and targeted therapies they require.

From a primary care perspective, the most useful mental health guidelines tackle the tough issues that cross a GP’s desk on a daily basis.9 Where are the best sources of self-help, self-monitoring, detailed illness descriptions, and family education to be found? Are there high quality e-health resources available?13 What options are available to a GP when patients become a danger to themselves or their reputations? How should a GP deal with poor compliance? What are the cost implications for patients of particular management plans (eg, costs of travel to specialist appointments)? What should the GP do when specialist services are not available? What are a GP’s responsibilities when the patient doesn’t return for follow-up appointments and/or medication monitoring? How should a GP document mental health consultations in their medical records? What other clinical or management resources are available? Is additional training required to deliver the therapies recommended in the guidelines?

While the recommendations presented by Mitchell et al,3 and the related technical summaries, do provide useful clues, insufficient attention to these practice-based issues risks an overall negative rating from the target audience.

Author detailsIan B Hickie, MD FRANZCP, Professor of Psychiatry and Executive Director1Grant A Blashki, MD, FRACGP, Senior Research Fellow,2 and Honorary Senior Lecturer, Health Services Research Department, King’s College London

1 Brain and Mind Research Institute, Sydney, NSW.

2 Department of General Practice and Program Evaluation Unit, University of Melbourne, Melbourne, VIC.

Correspondence: ianh@med.usyd.edu.au

References
  1. Goodwin GM. Consensus Group of the British Association for Psychopharmacology. Evidence-based guidelines for treating bipolar disorder: recommendations from the British Association for Psychopharmacology. J Psychopharmacol 2003; 17: 149-173. <PubMed>
  2. American Psychiatric Association. Practice guideline for the treatment of patients with bipolar disorder (revision). Am J Psychiatry 2002; 159 (4 Suppl): 1-50.
  3. Mitchell PB, Ball JR, Best JA, et al. The management of bipolar disorder in general practice. Med J Aust 2006; 184: 566-570. <eMJA full text>
  4. The Royal Australian and New Zealand College of Psychiatrists. Clinical practice guidelines. Available at: http://www.ranzcp.org/publicarea/cpg.asp (accessed Apr 2006).
  5. Ellis PM, Smith DAR. Treating depression: the beyondblue guidelines for treating depression in primary care. Med J Aust 2002; 176 (10 Suppl): S77-S83. <eMJA full text>
  6. Mant A, Rendle VA, Hall WD, et al. Making new choices about antidepressants in Australia: the long view 1975–2002. Med J Aust 2004; 181 (7 Suppl): S21-S24. <eMJA full text>
  7. Royal Australian and New Zealand College of Psychiatrists Clinical Practice Guidelines Team for Depression. Australian and New Zealand clinical practice guidelines for the treatment of depression. Aust N Z J Psychiatry 2004; 38: 389-407. <PubMed>
  8. National Health and Medical Research Council. Depression in young people. A guide for general practitioners. Canberra: AGPS, 1997.
  9. Hickie I. Primary care psychiatry is not specialist psychiatry in general practice. Med J Aust 1999; 170: 171-173. <eMJA full text> <PubMed>
  10. Hadjipavlou G, Mok H, Yatham LN. Pharmacotherapy of bipolar II disorder: a critical review of current evidence. Bipolar Disord 2004; 6: 14-25. <PubMed>
  11. Hickie IB, Pirkis JE, Blashki GA, et al. General practitioners’ response to depression and anxiety in the Australian community: a preliminary analysis. Med J Aust 2004; 181 (7 Suppl): S15-S20. <eMJA full text>
  12. Better mental health services for Australia. John Howard, Prime Minister. Media release 5 April 2006. Available at: http://www.pm.gov.au/news/media_releases/media_Release1858.html (accessed Apr 2006).
  13. Griffiths KM, Christensen H. Quality of web based information on treatment of depression: cross sectional survey. BMJ 2000; 321: 1511-1515. <PubMed>

(Received 19 Apr 2006, accepted 5 May 2006)

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