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Which substitution pharmacotherapy is most effective in treating opioid dependence?

Linda R Gowing, Robert L Ali and Jason M White
Med J Aust 2002; 176 (10): . || doi: 10.5694/j.1326-5377.2002.tb04523.x
Published online: 20 May 2002

Are levo acetyl methadol (LAAM) and buprenorphine as effective as methadone for substitution treatment of opioid dependence?


  • 1 Drug and Alcohol Services Council, Parkside, SA.
  • 2 Department of Clinical and Experimental Pharmacology, University of Adelaide, Adelaide, SA.



  • 1. Diagnostic and statistical manual of mental disorders: DSM-IV. Washington, DC: American Psychiatric Association, 1994.
  • 2. Ward J, Mattick RP, Hall W. Methadone maintenance treatment and other opioid replacement therapies. Amsterdam: Harwood Academic Publishers, 1998.

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