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Editorial

Defibrillation for out-of-hospital cardiac arrest

Strengthening that most important link in the "chain of survival"

MJA 2000; 172: 53-54

Cardiac arrest outside hospital is a common mode of unexpected death in our society. The arrest is usually caused by coronary artery disease, and indeed may be its first manifestation, occurring in apparently fit and well individuals. The causative arrhythmia is usually ventricular fibrillation, but by the time help arrives and the rhythm is recorded it has often degenerated into asystole.

In this issue of the Journal, Meyer et al1 present a detailed medical perspective of this problem, and outline the steps we need to take to improve the survival rate for victims of out-of-hospital cardiac arrest, particularly the "chain of survival" -- the critical links in the resuscitation process. When a cardiac arrest is witnessed, the first priority is defibrillation, but in most situations cardiopulmonary resuscitation (CPR) needs be undertaken before defibrillation.

The spectacular success of implantable defibrillators in terminating lethal arrhythmias2 in patients known to be at extreme risk of ventricular fibrillation raised the possibility that the same sensing technology and defibrillator waveforms might be incorporated into an external defibrillator, without the need for rhythm interpretation by a medical or paramedical attendant. Such devices were introduced over 10 years ago, and have been widely implemented, with results for successful defibrillation by junior ambulance officers that were as good as those of paramedics.3 By 1990, the New South Wales Ambulance Service had introduced semiautomatic defibrillators into all its frontline ambulances (ie, those not used for routine transport) to complement the care given by paramedics with manual defibrillators. Similar systems have since been initiated in other Australian States.

By 1991, the concept of public access defibrillation (PAD) was re-emerging. This idea was first conceived by the pioneer of prehospital coronary care, Frank Pantridge of Belfast,4 who developed a small but primitive defibrillator in the late 1960s which could be installed next to every fire extinguisher and used in the same way, simply and easily, and by whoever was closest. Pantridge asked the question "Is property more important than life?". With the re-emergence of this concept within the American Heart Association, the aim was to have semiautomatic defibrillators so widely available, and sufficient members of the public trained, that a person who suffered a cardiac arrest in a public place might have the benefit of a defibrillator before the arrival of an ambulance and when the chance of a successful outcome may be well over, rather than well under, 50%.5

Semiautomatic defibrillators are now deployed in what may seem to be the most unlikely places,5 and Australia has played a leading role. They were first installed in the QANTAS International fleet and in Australian airports during 1991.6 The long-term survival rate for people treated on the ground or in the air by QANTAS International staff is 32%,7 now exceeded by the seven of 14 (50%) for people treated by American Airlines staff over the past 18 months.8

Defibrillators are deployed widely in Chicago's O'Hare Airport and are available for public access. Deployment of public access defibrillators in airports is becoming commonplace, and Sydney's international and domestic terminals will be equipped with a system similar to Chicago's within months. Installation in airliners is becoming the industry standard throughout the world,8 with programs completed or under way for most major international and domestic airlines (including QANTAS and Ansett Domestic).

Use in airports and airliners has followed awareness of the fact that deaths from cardiac arrest in the air are far more common than deaths from aircraft crashes,7,8 while deaths in terminals of people undergoing unaccustomed exercise are more common than at other locations9 (except at sporting venues, where deaths in older spectators are common). Survival rates of 70% have been reported from the Melbourne Cricket Ground10 and in Las Vegas casinos:11 in both situations remote monitoring of crowd activity enables quick recognition, which, together with appropriate placement of personnel and devices, ensures a prompt response. Deployment of defibrillators in police cars, complementing the ambulance service in the environs of the Mayo Clinic, has increased community survival after cardiac arrest in Rochester, Minnesota, to near 50%.12

St John Ambulance, as the leading teacher of community resuscitation and first aid in Australia, has endorsed training in defibrillation with CPR, and is embarking on an ambitious program, through its training and operational arms, to make public access defibrillation widely available throughout the nation. Such a program must mesh with the existing professional ambulance service, and complement this by strengthening that most important earliest link in the "chain of survival" -- the prompt reversal of ventricular fibrillation by whoever can do so first, and fastest.

In strife-torn Belfast, Pantridge's idea lapsed because no system was available at the time for automatic recognition of ventricular defibrillation, so the device had to be used in the manual mode, and could have been used as a weapon. The introduction of safe semiautomatic defibrillators which will only operate in the presence of ventricular fibrillation has changed this situation. A satisfactory answer can now be given to Pantridge's question. As peace emerges in Ulster, the concept proposed by Pantridge and Geddes4 has taken firm root throughout the whole world.

Michael F O'Rourke
Professor of Medicine
University of New South Wales
and St Vincent's Hospital and Clinic, Sydney, NSW

  1. Meyer ADMcR, Cameron PA, Smith KL, McNeil JJ. Out-of-hospital cardiac arrest. Med J Aust 2000; 172: 73-76.
  2. Moss AJ, Hall WJ, Cannon DS, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med 1996; 335: 1933-1940.
  3. O'Rourke MF, Hall J. Pre-hospital cardiac arrest in New South Wales (1992). Aust N Z J Med 1994; 24: 619.
  4. Geddes JS, editor. The management of the acute coronary attack: the J Frank Pantridge Festschrift. London: Academic Press, 1986.
  5. Nichol G, Hallstrom AP, Kerber R, et al. American Heart Association Report on the Second Public Access Defibrillation Conference, April 17-19, 1997. Circulation 1998; 97: 1309-1314.
  6. Donaldson E, O'Rourke MF. Defibrillators on QANTAS aircraft. Med J Aust 1992; 156: 293.
  7. O'Rourke MF, Donaldson E, Geddes JS. An airline cardiac arrest program. Circulation 1997; 96: 2849-2853.
  8. Crewdson J. Code blue: survival in the sky. Chicago Tribune Aug 1, 1999: C1-C3.
  9. Becker L, Eisenberg M, Fahrenbruch C, Cobb L. Public locations of cardiac arrest: implication for public access defibrillation. Circulation 1998; 97: 2106-2109.
  10. Wassertheil J, Keane G, Fisher N, Leditschke JF. Cardiac arrest outcomes at the Melbourne Cricket Ground and Shrine of Remembrance using a tiered response strategy -- a forerunner to Public Access Defibrillation. Resuscitation 2000. In press.
  11. Valenzuela TD, Bjerke HS, Clark LL, et al. Rapid defibrillation by non-traditional responders. The Casino project. Acad Emerg Med 1998; 5: 414-415.
  12. White RD, Hankins DG, Bugliosi TF. Seven years' experience with early defibrillation by police and paramedics in an emergency medical services system. Resuscitation 1998; 30: 145-151.

©MJA 2000
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