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Multiresistant Escherichia coli in aged care: the gathering storm

Timothy J J Inglis and Christopher D Beer
Med J Aust 2011; 195 (9): . || doi: 10.5694/mja11.11202
Published online: 7 November 2011

The growing infection control challenges facing an ageing population

In this issue of the Journal, a study of multiresistant bacterial intestinal carriage by Stuart and colleagues adds important detail to the emerging picture of multiple antibiotic resistance in non-hospital settings.1 The higher colonisation rate they found for Escherichia coli than for vancomycin-resistant enterococci (VRE) or Clostridium difficile in residential aged care facilities is a timely reminder that our surveillance and infection control resources should not be exclusively targeted at VRE or C. difficile. The simultaneous presence of these potential pathogens in the same aged care population raises the ugly spectre of carriage of two or more resistant organisms. The risk of contemporaneous multiresistant E. coli, C. difficile-associated diarrhoea and faecal incontinence might be considered the perfect infection control storm.


  • 1 Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA.
  • 2 Western Australian Centre for Health and Ageing, University of Western Australia, Perth, WA.


Correspondence: tim.inglis@health.wa.gov.au

Competing interests:

No relevant disclosures.

  • 1. Stuart RL, Kotsanas D, Webb B, et al. Prevalence of antimicrobial-resistant organisms in residential aged care facilities. Med J Aust 2011; 195: 000-000. <MJA full text>
  • 2. Rooney PJ, O’Leary MC, Loughrey AC, et al. Nursing homes as a reservoir of extended-spectrum β-lactamase (ESBL)-producing ciprofloxacin-resistant Escherichia coli. J Antimicrob Chemother 2009; 64: 635-641.
  • 3. March A, Aschbacher R, Dhanji H, et al. Colonization of residents and staff of a long-term-care facility and adjacent acute-care hospital geriatric unit by multiresistant bacteria. Clin Microbiol Infect 2010; 16: 934-944.
  • 4. Rodriguez-Villalobos H, Bogaerts P, Berhin C, et al. Trends in production of extended-spectrum β-lactamases among Enterobacteriaceae of clinical interest: results of a nationwide survey in Belgian hospitals. J Antimicrob Chemother 2011; 66: 37-47.
  • 5. Naseer U, Sundsfjord A. The CTX-M conundrum: dissemination of plasmids and Escherichia coli clones. Microb Drug Resist 2011; 17: 83-97.
  • 6. Peirano G, Laupland KB, Gregson DB, Pitout JD. Colonization of returning travelers with CTX-M-producing Escherichia coli. J Travel Med 2011; 18: 299-303. doi: 10.1111/j.1708-8305.2011.00548.x.
  • 7. Partridge SR, Zong Z, Iredell JR. Recombination in IS26 and Tn2 in the evolution of multi-resistance regions carrying blaCTX-M-15 on conjugative IncF plasmids from Escherichia coli. Antimicrob Agents Chemother 2011 Aug 22 [Epub ahead of print].
  • 8. Tannock GW, Tiong IS, Priest P, et al. Testing probiotic strain Escherichia coli Nissle 1917 (Mutaflor) for its ability to reduce carriage of multidrug-resistant E. coli by elderly residents in long-term care facilities. J Med Microbiol 2011; 60: 366-370.
  • 9. Mody L, Bradley SF, Galecki A, et al. Conceptual model for reducing infections and antimicrobial resistance in skilled nursing facilities: focusing on residents with indwelling devices. Clin Infect Dis 2011; 52: 654-661.
  • 10. Caplan GA, Meller A, Squires B, et al. Advance care planning and hospital in the nursing home. Age Ageing 2006; 35: 581-585.

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