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Massive oxidative haemolysis and renal failure caused by high dose vitamin C

Matthew J Rees, Madeleine C Strach, Kate Burbury and Kelly-Anne Phillips
Med J Aust 2018; 209 (6): . || doi: 10.5694/mja17.00998
Published online: 17 September 2018

Clinical record


  • 1 Peter MacCallum Cancer Institute, Melbourne, VIC
  • 2 University of Melbourne, Melbourne, VIC


Correspondence: matthew.rees.md@gmail.com

Competing interests:

No relevant disclosures.

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  • 4. Huang YC, Chang TK, Fu YC, Jan SL. C for colored urine: acute hemolysis induced by high-dose ascorbic acid. Clin Toxicol (Phila) 2014; 52: 984.
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  • 6. Campbell GD, Steinberg MH, Bower JD. Letter: ascorbic acid-induced hemolysis in G-6-PD deficiency. Ann Intern Med 1975; 82: 810.
  • 7. Mehta JB, Singhal SB, Mehta BC. Ascorbic-acid-induced haemolysis in G-6-PD deficiency. Lancet 1990; 336: 944.

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