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	Daily dose (mg)
Drug	Start	Usual	Maximum	Adverse effects
Selective serotonin reuptake inhibitors (SSRIs)
Fluoxetine	20	20-40	80	Nausea, anorexia, weight loss, diarrhoea Headache Insomnia, somnolence Agitation, restlessness, anxiety Tremor, sweating Asthenia, lassitude SIADH Prolonged bleeding time Impaired orgasm, reduced libido
Paroxetine	20	20-40	50
Sertraline	50	50-100	200
Fluvoxamine	100	100-200	300
Citalopram	20	20-40	60
Reversible selective monoamine oxidase inhibitor (RIMA)
Moclobemide	300	300-600	600	Nausea, vomiting Headache Dizziness Insomnia Agitation Tremor
Serotonin-noradrenaline reuptake inhibitor (SNRI)
Venlafaxine	75	75-150	375	Nausea, anorexia, constipation Dizziness Dry mouth Insomnia, somnolence Sweating Asthenia Hypertension (at doses 225 mg) Abnormal ejaculation
5-HT2 antagonist/serotonin reuptake inhibitor
Nefazodone	100	200-400	600	Dry mouth Nausea Somnolence Dizziness Constipation Asthenia Lightheadedness Blurred vision
SIADH = syndrome of inappropriate antidiuretic hormone secretion.

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