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Drugs	Sedation	Postural hypotension	Anticholinergic effects	Extrapyramidal side effects	Other*
Phenothiazines
Chlorpromazine	+++	+++	++	++	Photosensitivity
Pericyazine	+++	++	+++	++
Thioridazine	+++	++	++	++	Severe decrease in libido Retinal pigmentation Cardiotoxicity in overdose
Fluphenazine
Trifluoperazine	++	+	+	++
Butyrophenones
Haloperidol	+	+	+	+++	Young men most at risk of side effects Acute dystonic reactions
Thioxanthines
Thiothixene	++	+	+	+++	Slightly activating
Diphenylbutyl
Pimozide	+	+	+	+++	Sudden death due to arrhythmia at high doses ECG monitoring of benefit
Atypical neuroleptic agents
Clozapine	++++	+++	+++	+	Agranulocytosis Weight gain
Risperidone	+	++	+	+	Extrapyramidal symptoms increase in higher doses
Olanzapine	++	+	++	+	Weight gain
*A more comprehensive discussion of side effects is available in the Psychotropic drug guidelines.

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