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| Some medical conditions associated with psychotic symptoms
Neurological disorders
- Infections; especially viral, including HIV
- Cerebrovascular disease; linked to late-onset psychosis
- Cerebral trauma; usually with long latency
- Multiple sclerosis; especially when many periventricular lesions
are present
- Huntington's disease; psychotic symptoms in 5%-10% of cases
- Epilepsy; especially complex partial seizures
- Neoplasms; most commonly of the temporal lobe and cingulate gyrus
- Other space occupying lesions; e.g., abscesses
Endocrine, metabolic and autoimmune disorders
- Cushing's syndrome; psychosis occurs in up to 20% of
patients
- Hyperthyroidism and hypothyroidism
- Hyperparathyroidism; psychosis may occur with a clear sensorium
- Porphyria; acute intermittent porphyria and porphyria variegata
- Vitamin B12 deficiency; depression more common
- Systemic lupus erythematosus, and associated steroid-induced
psychosis
- Wilson's disease
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