MJA: Metrebian et al., Box 3

3:·Number of patients (%) giving positive urine tests over three-month periods

	6 Month data (n=36)
Illicit drug	0-3 months	3-6 months	P
Tranquillisers	20 (55.6%)	17 (47.2%)	0.5
Amphetamines	5 (13.8%)	1 (2.8%)	0.5
Barbiturates	1 (2.8%)	1 (2.8%)	0.5
"Crack"/cocaine	12 (33.3%)	8 (22.2%)	0.3
Opiates (codeine/morphine)	3 (23.1%)*	2 (15.4%)*	0.5

12 Month data (n=30)

Illicit drug 0-3 months 3-6 months 6-12 months P (0-3 to 6-12) P (3-6 to 6-12)

Tranquillisers 18 (60.0%) 11 (36.7%) 12 (40%) 0.27 0.3

Amphetamines 4 (13.3%) 0 1 (3.3%) 0.31 0.5

Barbiturates 1 (3.3%) 1 (3.3%) 1 (3.3%) 0.5 0.5

"Crack"/cocaine 10 (33.3%) 7 (23.3%) 8 (26.7%) 0.38 0.4

Opiates (codeine/morphine) 3 (30%)† 0† 2 (20%)† 0.5 0.25

*Data for those receiving injectable methadone (n=13).
†Data for those receiving injectable methadone (n=10).

N.B.
6 month data: Missing data for 4 patients, 8 discontinued treatment.
12 month data: Missing data for 5 patients, 25 discontinued treatment.

The Medical Journal of Australia eMJA

	12 Month data (n=30)
Illicit drug	0-3 months	3-6 months	6-12 months	P (0-3 to 6-12)	P (3-6 to 6-12)
Tranquillisers	18 (60.0%)	11 (36.7%)	12 (40%)	0.27	0.3
Amphetamines	4 (13.3%)	0	1 (3.3%)	0.31	0.5
Barbiturates	1 (3.3%)	1 (3.3%)	1 (3.3%)	0.5	0.5
"Crack"/cocaine	10 (33.3%)	7 (23.3%)	8 (26.7%)	0.38	0.4
Opiates (codeine/morphine)	3 (30%)†	0†	2 (20%)†	0.5	0.25