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Ian M Whyte, Andrew H Dawson, Nicholas A Buckley, Gregory L Carter and Catherine M Levey
Abstract - Introduction - Service structure - Philosophy and strategies - Nursing perspective - Psychiatric perspective - Medical perspective - Outcomes and resource use - Discussion - Acknowledgements - References - Authors' details
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©MJA1997
With a few exceptions, deliberate self-poisoning is managed on an
ad-hoc basis in Australian hospitals. Commonly, the patient
is managed in the emergency department and, if required, admission
occurs under the general physician of the day or under the specialty
which best corresponds to the patient's toxicological problem.
Other models include medical management for most patients occurring
entirely within the emergency department/intensive care axis. In
one centre, 30% of patients with deliberate self-poisoning were not
formally admitted.5 In many
centres, expertise in toxicology comes from outside the service
providing the patient care (e.g., from Poisons Information
Centres).
In these models of management, not every patient with deliberate
self-poisoning receives formal psychiatric assessment. Despite
evidence that psychiatric intervention after parasuicide is
worthwhile,6 psychiatric
resources are commonly concentrated on those patients who require
admission and those who have the most medically severe poisoning.7 However, significant
suicidal risk is present for many patients with toxicologically
"trivial" poisonings.
All deliberate self-poisoning patients are formally admitted under
the HATS clinical toxicologist, who retains primary responsibility
for care during the whole admission. A toxicology data collection
form was developed which is also the formal admission record. The
psychiatry team assess all patients with deliberate self-poisoning
and, on request, other poisonings. Referral to the drug and alcohol
service occurs as necessary. The patient is determined as medically
fit for discharge by the toxicologist and the decision on appropriate
discharge destination is made by the psychiatrist. Medical
follow-up, when required, is the responsibility of the
toxicologist.
A relational database for collecting data on poisoned patients4 was written (by I M W) in late 1986.
The complexity of this database has progressively increased and an
extensive psychiatric component (written by G L C) became
operational in January 1996.
HATS was transferred to the Newcastle Mater Misericordiae Hospital
in 1991 and took on an Area role (population, 385 000). All poisoning
cases are transferred, either directly or after assessment at a
closer hospital, to the Newcastle Mater Misericordiae Hospital
unless they are too ill. If they are admitted to another hospital, they
are admitted under the care of HATS. In practice, this relates to
critically ill patients who are admitted to the intensive care unit at
the presenting hospital under the care of the toxicologist from HATS,
and discharged directly from that unit or transferred to the
Newcastle Mater Misericordiae Hospital if they need more inpatient
care after their intensive care stay.
HATS provides a 24-hour telephone consulting service for the Upper
and Lower Hunter Areas (population, 100 000) and a tertiary referral
service when required. The clinical pathway for this managed care is
shown in Figure 1.
HATS medical management is provided by a full time equivalent
clinical toxicologist (currently two clinical pharmacologists)
and a registrar in clinical toxicology. The after hours service is
provided by the two clinical pharmacologists with the addition of
another clinical pharmacologist and a drug and alcohol specialist
with an interest in toxicology. Every toxicology admission is seen by
the medical team (at least once a day), seven days a week.
HATS psychiatric care is provided by a psychiatrist, a psychiatry
registrar and a clinical nurse consultant in psychiatry. An after
hours service is provided by part of an area roster of psychiatry
registrars and four to six "second on call" psychiatrists. Every
deliberate self-poisoning admission is seen by the psychiatry team
(at least once a day), seven days a week. Even when the patient is
consciously or cognitively impaired, our practice is to begin the
psychiatric assessment by obtaining a collateral history from
family/friends and health care workers before proceeding with
individual psychiatric assessment. If the patient presents with a
toxicologically trivial poisoning after 5 pm or on weekends (which
would allow discharge before the routine morning psychiatric
review) then the psychiatric registrar on call will come in to do the
assessment and decide on appropriate discharge destination.
In 1995 there were 736 admissions to HATS (see Box 1). The median
(range) hospital stay is calculated because the data are not normally
distributed. The lower quartile is at 10.5 hours and the upper
quartile at 27.5 hours. The distribution of hospital stay for
deliberate self-poisoning patients is shown in Figure 2. In 1994-1995, for all hospitals with
an emergency department in the Greater Newcastle area, deliberate
self-poisoning comprised 1.2% of medical admissions; most
presented to Newcastle Mater Misericordiae Hospital, where they
comprised 7.3% of medical admissions. Of the 520 deliberate
self-poisoning admissions who received formal psychiatric
assessment, 492 (94.6%) had had one or more formal diagnoses11 made of psychiatric disorder,
personality disorder or other condition ("V" codes11).
Average length of stay data for HATS compared with national data and
all NSW public hospitals are shown in Boxes 2 and 3, respectively. Box 2
compares data derived from the HATS database for 1991-1994 with
national data for 1992 (the most recent year available). Box 3
presents data from the NSW Health Department Inpatient Statistics
Collection (1994-1995), and compares deliberate self-poisoning
admissions to Newcastle Mater Misericordiae Hospital with the mean
for all public hospitals in NSW. The data from Newcastle Mater
Misericordiae Hospital in Box 3 are not derived from the HATS
database, but rather from independent coding by the Medical Records
Department of the Newcastle Mater Misericordiae Hospital according
to ICD-9-CM.10 Both
comparisons show a substantial reduction in bed stay for HATS. Since
those patients not formally admitted at other hospitals are likely to
be short stay presentations and thus not reported in the Inpatient
Statistics Collection, we further analysed HATS data for 1993-1995.
For all admissions average length of stay was 1.5 days; for all
admissions with a hospital stay greater than 12 hours (72.6% of
admissions) average length of stay was 1.69 days; for all admissions
that required intensive care admission (16.8%), average length of
stay was 2.59 days.
There has been no evidence that reduced bed stay has compromised
patient care, as mortality from deliberate self-poisoning during
this period (1987-1995) has been 0.6% (24 deaths in 3856 deliberate
self-poisoning admissions; 95% CI, 0.4-0.9). Most of these patients
had an out-of-hospital cardiac arrest and death was inevitable on
presentation.4 NSW Health
Department data for 1992 (the most recent year for which death data are
available) show 13 inpatient deaths in 2876 admissions in NSW (0.5%;
95% CI, 0.2-0.8). HATS data for 1992 show one inpatient death in 512
deliberate self-poisoning admissions (0.2%; 95% CI, 0.0-1.1).
These proportions are not significantly different (chi-squared = 2.04; P = 0.36).
Standardised mortality ratios for suicide in NSW show the Hunter Area
has no greater all-cause suicide mortality.13
HATS' prospective data collection on all presentations in a defined
population is a very powerful tool for observational research. We
have been able to identify public health issues related to patterns of
drug use,14,15 relative
toxicity of drugs within classes16-18 and the impact of safety
packaging of medications.19
The NSW Health Department, as part of its health outcomes strategy,
has provided funds to HATS to develop the management model (and the
database) so that it can be trialled at other centres in NSW.
It could be argued that shorter length of stay in the Hunter is due to our
policy of admitting all patients with deliberate self-poisoning
regardless of severity. However, the greatest difference in average
length of stay occurs in those patients with complications or
comorbidities (Boxes 2 and 3), who require admission under any
policy. Figure 2 shows that 90% of all our
patients stay in hospital for less than 50 hours, which is less than the
average length of stay for uncomplicated poisoning in NSW public
hospitals (Box 3). In addition, HATS bed stay for all admissions
(complicated and uncomplicated) after excluding those admitted for
less than 12 hours (27.3% of presentations) is still shorter than the
average length of stay for uncomplicated admissions to all NSW
hospitals. The average length of stay for HATS admissions requiring
intensive care is more than two days shorter than the average length of
stay for all complicated admissions to NSW hospitals.
The model of management of self-poisoning described in this article
is, we believe, unique in Australia. The differences we have
identified in this model are:
We argue that all patients who present with deliberate
self-poisoning should be admitted for several reasons:
This model has resulted in a substantial and significant reduction in
bed stay, which increases beds available for other purposes in the
Area. There are two ways of calculating the monetary cost if funding
were on a diagnosis-related group (DRG) basis. The first is to
multiply the bed-days saved by the DRG cost of a bed-day, as in Box 2 and
Box 3. The second is to assume the saved beds will be occupied by
patients attracting further DRG funding. Assigning a monetary value
to this is not possible. It is clear, however, that based on DRG funding
these saved bed-days are worth more to the Area than the cost of running
the service.
The reduction in bed stay has not been accompanied by a worsening in
outcome, as defined by in-hospital mortality from deliberate
self-poisoning or standardised mortality ratios for all-cause
suicide. While the number of admissions to HATS in 1992 appears
disproportionate, it is consistent with the proportion of
admissions to other major hospitals1,2 and reflects our policy of
admitting all patients who present with deliberate self-poisoning.
It appears likely the Department of Health figures for admissions
significantly underestimate the number of presentations for
deliberate self-poisoning to NSW hospitals. If so, while the
magnitude of the saving per admission may be uncertain, on a
State-wide basis the potential savings from implementing our model
are even greater.
Without further data, determining the reasons for the shorter
average length of stay is not possible, but anecdotal comparisons
with other hospitals suggest the following
possibilities:
Our current model of management has evolved using the skills and
experience of those interested in poisoning in Newcastle. The only
new position created was the registrar position in clinical
pharmacology. We do not believe, however, that replicating the model
or its outcomes is dependent on replicating our subspecialty mix.
Nevertheless, the identification of a team to manage poisoning is
crucial. In many health areas the emergency physicians may be the
logical choice for such a team. This would require an extension of
admitting rights into the general hospital or a collaborative
venture with an identifiable medical team. A specific group of
psychiatrists is also required.
We believe that Area Health Services should consolidate acute
toxicology services. A potential disadvantage of consolidation is
loss of skills in the management of toxicological problems in other
hospitals in the Area. This could be offset by making the service part
of registrar and nursing training rotations. The advantages of
consolidation include:
The efficiencies of this model are a product of the reorganisation of
largely existing resources to provide a multidisciplinary team
approach to the management of poisoned patients. The provision of
care is based on a philosophy that these patients are entitled to a
legitimate sick role. The major stumbling block to establishing a
similar dedicated service is in making the decision to reorganise
existing services. As House et al. state, after reviewing services in
the United Kingdom, "there is much to recommend in clinical
diversity, but nothing to recommend [in] unplanned and
incoordinated service provision".6
Discipline of Clinical Pharmacology, University of Newcastle,
Newcastle, NSW.
Reprints: Dr I M Whyte, Department of Clinical Toxicology and
Pharmacology, Newcastle Mater Misericordiae Hospital, Locked Bag
7, Hunter Regional Mail Centre, NSW 2310.
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©MJA 1997
<URL: http://www.mja.com.au/>
© 1997 Medical Journal of Australia.
Abstract
Objective: To describe the development and activity
of a multidisciplinary service to manage self-poisoning.
Design: Descriptive, comparative study with
prospective data collection.
Setting: Regional toxicology treatment centre in
the Hunter area of New South Wales (NSW) with primary and secondary
referral service to 385 000 people and tertiary referral service to a
further 100 000.
Patients: All patients (1987-1995) with poisoning
or envenomation presenting to the Hunter Area Toxicology Service
(HATS).
Main outcome measures: Average length of stay for
HATS compared with national and NSW hospitals; mortality data for
HATS compared with NSW.
Results: Average length of stay for HATS was
0.53-1.22 days shorter than for all Australian hospitals,
potentially saving 518 bed-days, valued at $468 000 per year. Average
length of stay was 0.94-3.39 days shorter than for all NSW hospitals,
saving 1470 bed-days at $1.4 million per year. Inpatient mortality
(0.2%; 95% confidence interval, 0.0-1.1) was not significantly
different from NSW (0.5%; 95% CI, 0.2-0.8). Standardised mortality
ratios showed no greater all-cause suicide mortality.
Conclusions: In our centralised model for managing
self-poisoning, all toxicology patients in an area health service
are diverted to one hospital, where all patients with deliberate
self-poisoning are admitted under the one multidisciplinary team,
and all receive psychiatric assessment. This model has
substantially reduced bed stay, with considerable savings to the
Hunter Area Health Service manifested as an increase in beds
available for other purposes.
Introduction
Estimates of admissions for deliberate self-poisoning vary from 1%1 up to 5%2 of public hospital admissions. More
than 50% of these admissions occur between 6 pm and 2 am.3 Deliberate self-poisoning
(including carbon monoxide) is the cause of death in 42% of suicides.4
Service structure
In 1986 the Department of Clinical Pharmacology, then located at the
Royal Newcastle Hospital, was requested to manage deliberate
self-poisoning and other toxicology patients. The Hunter Area
Toxicology Service (HATS) was established jointly by the Department
of Clinical Toxicology and Pharmacology and the Department of
Liaison Psychiatry in January 1987. The only increase in staff was one
registrar position in clinical pharmacology.
Philosophy and strategies
HATS was established with the premise that deliberate
self-poisoning is a presenting symptom for an underlying
psychiatric disorder, personality disorder or psychosocial
problem that requires assessment and intervention. A distinction is
made between "drug overdose" (exposure to an amount of drug or toxin
sufficient to cause harm) and the more inclusive term "deliberate
self-poisoning", which also includes toxicologically trivial
exposures. All admissions are formally discussed at a weekly
multidisciplinary meeting where medical and psychiatric
management is reviewed. When appropriate, individualised
management plans are discussed for patients who have frequent
presentations.
Nursing perspective
Nursing care of deliberate self-poisoning patients uses a combined
medical and behavioural model. The staff recognise that patients
with deliberate self-poisoning are entitled to a legitimate "sick
role"8 and use a
non-judgemental approach to patients and their relatives.
Retention of patients for the full duration of treatment can be
increased by emphasising the need for medical review and treating
deliberate self-poisoning patients in a similar manner to other
medical patients. In the acute phase of the admission, patients are
kept in hospital pyjamas and their street clothes removed. Patients
with catheters or intravenous cannulas often have these devices kept
in situ until their mental state is assessed and their
discharge destination is determined by the psychiatric team. The
involvement of family and friends in helping to orientate and support
the patient can lessen the nursing burden and improve compliance.
Psychiatric perspective
Psychiatric care of deliberate self-poisoning patients is aimed at
maintaining the safety of the patient (and staff), enhancing
compliance with decontamination and other medical treatment,
psychological support, the initiation of treatment for specific
indications (e.g., delirium, psychosis and relationship
problems), and coordination of psychiatric follow-up. The
incorporation of a psychiatry team in HATS allows for very early
intervention in deliberate self-poisoning, in contrast to
consulting the psychiatrist after completion of medical
management.
Medical perspective
The primary aim in the treatment of poisoned patients is to reduce
mortality and early and late morbidity. The secondary aim of
treatment is to reduce hospital stay and use hospital resources
efficiently. This is accomplished by an active education program9 focused on evidence-based
management, good supportive care and actively discouraging
punitive medical procedures.
Outcomes and resource use
The NSW Health Department Inpatient Statistics Collection uses
average length of stay (with a minimum bed stay for a formal admission
defined as one day). Examination of medical records data for patients
with self-poisoning (ICD-9-CM10
codes E950-E959) admitted to the Royal Newcastle Hospital in
1985 and 1986 showed an average length of stay of 3.88 days. For 1987,
when HATS began to operate, the average length of stay for this group of
patients had decreased to 2.75 days and for 1988 to 1.4 days.

Discussion
There are difficulties in comparing data collected by clinicians
with a particular interest in a group of patients and national data
derived from ICD-9 coding from all hospitals in Australia. The main
difficulty is the potential for ascertainment bias. For example, it
is possible the national data contain significant numbers of
patients without true deliberate self-poisoning, who have a longer
length of stay. This may make our comparisons less robust. However,
the data for NMMH in Box 3 are the official data requested by the NSW
Department of Health for inclusion in the NSW Inpatient Statistics
Collection and are thus directly comparable to data from other NSW
public hospitals.

Acknowledgements
We would like to acknowledge the support of nursing staff in the
Intensive Care Unit, the Emergency Department and Ward 5E at the
Newcastle Mater Misericordiae Hospital. The Hunter Area Toxicology
Service has also received considerable support from the Mental
Health Epidemiology Group (NSW Department of Health) and the Chief
Executive Officer of the Hunter Area Health Service, Dr Timothy
Smyth. Some of the later development of this service was supported by a
NSW Health Department Health Outcomes grant and a grant from the
Hunter Area Health Service.
References
(Received 26 Aug 1996, accepted 3 Apr 1997)
Authors' details
Newcastle Mater Misericordiae Hospital, Newcastle, NSW.
Ian M Whyte, FRACP, Senior Staff Specialist and Director,
Department of Clinical Toxicology and Pharmacology.
Andrew H Dawson, FRCP, FRACP, Staff Specialist, Department
of Clinical Toxicology and Pharmacology.
Gregory L Carter,
FRANZCP, Senior Staff Specialist, Department of Liaison
Psychiatry.
Catherine M Levey, RN, ICUCert, Clinical Nurse
Specialist, Intensive Care Unit.
Nicholas A Buckley, FRACP, Lecturer.
E-mail: mdimw@cc.newcastle.edu.au