eMJA: Hand–foot syndrome after treatment with docetaxel

Snapshot

Hand–foot syndrome after treatment with docetaxel

Chitra Sivaramamoorthy, Eddy S Thientosapol and Martin H Tattersall

MJA 2009; 191 (1): 40

A woman with metastatic breast cancer developed diarrhoea, vomiting, and hand and foot discomfort within about 10 days of ceasing therapy with capecitabine and starting docetaxel therapy. The palms of both hands and feet were inflamed and tender, with confluent blanching erythematous areas (Figure). Extensive desquamation occurred from Day 12 to Day 19 after admission, with return to normal skin by Day 30.

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