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The prevention and management of osteoporosis

Consensus statement

Australian National Consensus Conference 1996

OSTEOPOROSIS is a condition of low bone mass leading to greater bone fragility and an increase in fractures, especially among older Australians. It is a major cause of fractures, producing considerable morbidity and mortality. The current cost to the community of osteoporotic fractures among Australians over 60 years of age is estimated at $779,000,000 annually. With an ageing population the problem will grow dramatically unless successful strategies for preventing and treating osteoporosis are devised.

To date, there has been little consensus on a number of issues relating to the prevention and management of osteoporosis. The principal indicator of the disease is bone density as measured by bone densitometry, but the place of population or high-risk screening is unclear, as is the role of alternative diagnostic tools such as ultrasound. Hormone replacement therapy is first line treatment for postmenopausal women, but its effects in the long term are not known; the roles of bisphosphonates, calcitriol, calcium and exercise are less certain. Little is known about effectively managing osteoporosis in men. Falls prevention and some other risk factors for fracture need to be addressed, as they may be as important as improving bone density in preventing fractures.

After successful National Consensus Conferences in 1991 (on the management of hyperlipidaemia) and 1993 (on the management of hypertension), the Pharmaceutical Benefits Advisory Committee of the Department of Health and Family Services decided to sponsor another to address the prevention and management of osteoporosis. The conference was held in Canberra on 23-24 October 1996 and was supported by the Pharmaceutical Education Program. The co-sponsors were the Australian and New Zealand Bone and Mineral Society, the Australian Pharmaceutical Manufacturers' Association, Osteoporosis Australia, the Australasian Menopause Society, the Royal Australian College of General Practitioners, the Royal Australasian College of Physicians and the Royal Australian College of Obstetricians and Gynaecologists.

The objectives of the conference were to produce a consensus statement that would:

  • form the basis for development of clinical guidelines on the appropriate prevention, diagnosis and treatment (drug and non-drug) of osteoporosis;

  • provide advice to the Pharmaceutical Benefits Advisory Committee (PBAC) about the listing on the Pharmaceutical Benefits Scheme of pharmaceuticals for the prevention and treatment of osteoporosis; and

  • provide advice to health policy makers about interventions for the prevention, diagnosis and management (drug and non-drug) of osteoporosis.
The Australian National Consensus Conference 1996 used a consensus development process to achieve these objectives.

At the conference, a faculty of speakers expert in preventing and managing osteoporosis presented evidence to a Consensus Panel and conference delegates. The Panel included experts in osteoporosis-related fields, including epidemiology, endocrinology, rheumatology, orthopaedics, obstetrics and gynaecology, biochemistry, general practice, dietetics, physiotherapy, and the consumer movement. The speakers were asked to rate the strength of the evidence, from meta-analysis of all relevant randomised controlled trials through to expert opinion. From this evidence, the Panel drafted a statement as a set of answers to questions posed to it by the organising committee. The draft statement was then discussed and debated on the floor of the conference, and the resulting amendments and additions were considered for the final consensus statement.

The Consensus Statement is intended to guide medical practitioners in preventing and managing osteoporosis. The continuing uncertainty in many areas of prevention and management highlights the need for further research.

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The Medical Journal of Australia
Supplement to the 7 July issue (MJA 1997; 167: S1-S15)

 

Commonwealth Department of Health and Family Services

 

This publication was funded through the Pharmaceutical Education Program, a Federal Government initiative to promote the quality use of medicines

 


Consensus Panel

 

Contents List

 

Contact for printed copies


 

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©1997 Medical Journal of Australia.